TGT's OsteoGen bioreactors impart perfusion through cell seeded cylindrical scaffolds. Applications include investigating cell function, modulating the growth and development of engineered tissues, or acting as a test bed for drug and regenerative medicine technologies. The OsteoGen employs the 6Ocr-83 pulsatile hydrostatic pressure sitmulator to deliver user defined sine pressure wave forms of physiological magnitude, with a maximum pressure of 200 mmHg. The 6Ocr-83 is integrated with a computer controlled mean flow pump and is capable of low or high flow configurations. Researchers are currently utilizing these systems in a wide range of research areas including:
1O OsteoGen
The 1O system has been designed as a single sample bioreactor system that is able to support a wide range of cell and tissue growth experiments via user defined stimulation protocols. This chamber can accommodate a single sample with a maximum size of 10 mm diameter x 10 mm thick. Optional features such as; transducers, non-contact micrometers, pressure sensors, etc., and/or modules to customize the instrument to specific needs can be added to accomodate the research application.
12O OsteoGen
The 12O system has been designed as a single sample multi-chamber bioreactor system that is able to support a wide range of cell and tissue growth experiments via user defined stimulation protocols. This chamber can accommodate a single sample with a maximum size of 10 mm diameter x 10 mm thick. A custom manifold integrates up to 12 chambers on a common flow loop with a single stimulator and mean flow pump. However, if the application does not require pulsatile hydrostatic pressure the multi-chamber system can operate with individual flow loops. Optional features such as; transducers, non-contact micrometers, pressure sensors, etc., and/or modules to customize the instrument to specific needs can be added to accomodate the research application.
Click here to download a OsteoGen Brochure (Adobe PDF 21kb)
| BONE | ||
| Key: S=Standard, A=Available, - = not available | ||
| CHAMBERS | 1O | 12O |
| Individual growth chamber | S | S |
| 12 parallel growth chambers | - | A |
| Max construct size: 6 mm diameter by 10 mm long | S | S |
| STIMULATION | ||
| Pulsatile fluid flow stimulator | A | A |
| CONTROLS | ||
| Controller software, computer, and monitor | A | A |
| Power supplies and cabling | A | A |
| Mean flow control | A | A |
| Dynamic flow control | A | A |
| TISSUE MONITORING | ||
| Non-contact flow sensors | A | A |
| Catheter pressure transducers | A | A |
| ACCESSORIES | ||
| Media reservoir | S | S |
| Incubator | A | A |
| BENEFITS | ||
| All-autoclavable components | S | S |
| Excellent sample access | S | S |
| Medium change without operning chamber via luer fittings | S | S |
| Increased sterility with fast and clean sample change and access | S | S |
| Lightweight design for easy handling | S | S |
| Easily cleaned surface finishes | S | S |
| Compact design for fit in standard incubators | S | S |
| 100% satisfaction guaranteed warranty | S | S |
